SUMOylation Regulates Insulin Exocytosis Downstream of Secretory Granule Docking in Rodents and Humans

OBJECTIVE: The reversible attachment of small ubiquitin-like modifier (SUMO) proteins controls target localization and function. We examined an acute role for the SUMOylation pathway in downstream events mediating insulin secretion. RESEARCH DESIGN AND METHODS: We studied islets and β-cells from mic...

Descripción completa

Detalles Bibliográficos
Autores principales: Dai, Xiao-Qing, Plummer, Greg, Casimir, Marina, Kang, Youhou, Hajmrle, Catherine, Gaisano, Herbert Y., Manning Fox, Jocelyn E., MacDonald, Patrick E.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046844/
https://www.ncbi.nlm.nih.gov/pubmed/21266332
http://dx.doi.org/10.2337/db10-0440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046844/
https://www.ncbi.nlm.nih.gov/pubmed/21266332
http://dx.doi.org/10.2337/db10-0440

Ejemplares similares