Natural Killer Cells From Children With Type 1 Diabetes Have Defects in NKG2D-Dependent Function and Signaling

OBJECTIVE: Natural killer (NK) cells from NOD mice have numeric and functional abnormalities, and restoration of NK cell function prevents autoimmune diabetes in NOD mice. However, little is known about the number and function of NK cells in humans affected by type 1 diabetes. Therefore, we evaluate...

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Detalles Bibliográficos
Autores principales: Qin, Huilian, Lee, I-Fang, Panagiotopoulos, Constadina, Wang, Xiaoxia, Chu, Alvina D., Utz, Paul J., Priatel, John J., Tan, Rusung
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Immunology and Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046846/
https://www.ncbi.nlm.nih.gov/pubmed/21270236
http://dx.doi.org/10.2337/db09-1706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046846/
https://www.ncbi.nlm.nih.gov/pubmed/21270236
http://dx.doi.org/10.2337/db09-1706

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