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Natural Killer Cells From Children With Type 1 Diabetes Have Defects in NKG2D-Dependent Function and Signaling
OBJECTIVE: Natural killer (NK) cells from NOD mice have numeric and functional abnormalities, and restoration of NK cell function prevents autoimmune diabetes in NOD mice. However, little is known about the number and function of NK cells in humans affected by type 1 diabetes. Therefore, we evaluate...
Autores principales: | Qin, Huilian, Lee, I-Fang, Panagiotopoulos, Constadina, Wang, Xiaoxia, Chu, Alvina D., Utz, Paul J., Priatel, John J., Tan, Rusung |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046846/ https://www.ncbi.nlm.nih.gov/pubmed/21270236 http://dx.doi.org/10.2337/db09-1706 |
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