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Neuronal Sirt3 Protects against Excitotoxic Injury in Mouse Cortical Neuron Culture
BACKGROUND: Sirtuins (Sirt), a family of nicotinamide adenine nucleotide (NAD) dependent deacetylases, are implicated in energy metabolism and life span. Among the known Sirt isoforms (Sirt1-7), Sirt3 was identified as a stress responsive deacetylase recently shown to play a role in protecting cells...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046953/ https://www.ncbi.nlm.nih.gov/pubmed/21390294 http://dx.doi.org/10.1371/journal.pone.0014731 |