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The Formation of the Bicoid Morphogen Gradient Requires Protein Movement from Anteriorly Localized mRNA

The Bicoid morphogen gradient directs the patterning of cell fates along the anterior-posterior axis of the syncytial Drosophila embryo and serves as a paradigm of morphogen-mediated patterning. The simplest models of gradient formation rely on constant protein synthesis and diffusion from anteriorl...

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Detalles Bibliográficos
Autores principales: Little, Shawn C., Tkačik, Gašper, Kneeland, Thomas B., Wieschaus, Eric F., Gregor, Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046954/
https://www.ncbi.nlm.nih.gov/pubmed/21390295
http://dx.doi.org/10.1371/journal.pbio.1000596