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Crystal Structure Analysis of the Polysialic Acid Specific O-Acetyltransferase NeuO
The major virulence factor of the neuroinvasive pathogen Escherichia coli K1 is the K1 capsule composed of α2,8-linked polysialic acid (polySia). K1 strains harboring the CUS-3 prophage modify their capsular polysaccharide by phase-variable O-acetlyation, a step that is associated with increased vir...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046976/ https://www.ncbi.nlm.nih.gov/pubmed/21390252 http://dx.doi.org/10.1371/journal.pone.0017403 |