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Crystal Structure Analysis of the Polysialic Acid Specific O-Acetyltransferase NeuO

The major virulence factor of the neuroinvasive pathogen Escherichia coli K1 is the K1 capsule composed of α2,8-linked polysialic acid (polySia). K1 strains harboring the CUS-3 prophage modify their capsular polysaccharide by phase-variable O-acetlyation, a step that is associated with increased vir...

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Detalles Bibliográficos
Autores principales: Schulz, Eike C., Bergfeld, Anne K., Ficner, Ralf, Mühlenhoff, Martina
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046976/
https://www.ncbi.nlm.nih.gov/pubmed/21390252
http://dx.doi.org/10.1371/journal.pone.0017403