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Processing of metacaspase into a cytoplasmic catalytic domain mediating cell death in Leishmania major

Metacaspases are cysteine peptidases that could play a role similar to caspases in the cell death programme of plants, fungi and protozoa. The human protozoan parasite Leishmania major expresses a single metacaspase (LmjMCA) harbouring a central domain with the catalytic dyad histidine and cysteine...

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Detalles Bibliográficos
Autores principales: Zalila, Habib, González, Iveth J, El-Fadili, Amal Kuendig, Delgado, Maria Belen, Desponds, Chantal, Schaff, Cédric, Fasel, Nicolas
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047009/
https://www.ncbi.nlm.nih.gov/pubmed/21166905
http://dx.doi.org/10.1111/j.1365-2958.2010.07443.x