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Development of Second-Generation VEGFR Tyrosine Kinase Inhibitors: Current Status
The vascular endothelial growth factor (VEGF) signaling pathway appears to be the dominant pathway involved in tumor angiogenesis, providing a rationale for targeting the VEGF receptors (VEGFR-1, -2, and -3) in the treatment of cancers. In particular, VEGF signaling is thought to be important in ren...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Current Science Inc.
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047052/ https://www.ncbi.nlm.nih.gov/pubmed/21318618 http://dx.doi.org/10.1007/s11912-011-0154-3 |