Cell- and region-specific miR30-based gene knock-down with temporal control in the rat brain

BACKGROUND: RNA interference (RNAi) emerges as a powerful tool to induce loss-of-function phenotypes. In the context of the brain, gene manipulation is best targeted to specific subsets of cells in order to achieve a physiologically relevant outcome. Polymerase II-based viral expression systems can...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Beihui, Xu, Haibo, Paton, Julian FR, Kasparov, Sergey
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047298/
https://www.ncbi.nlm.nih.gov/pubmed/21134262
http://dx.doi.org/10.1186/1471-2199-11-93

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047298/
https://www.ncbi.nlm.nih.gov/pubmed/21134262
http://dx.doi.org/10.1186/1471-2199-11-93

Ejemplares similares