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Cell- and region-specific miR30-based gene knock-down with temporal control in the rat brain
BACKGROUND: RNA interference (RNAi) emerges as a powerful tool to induce loss-of-function phenotypes. In the context of the brain, gene manipulation is best targeted to specific subsets of cells in order to achieve a physiologically relevant outcome. Polymerase II-based viral expression systems can...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047298/ https://www.ncbi.nlm.nih.gov/pubmed/21134262 http://dx.doi.org/10.1186/1471-2199-11-93 |