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Structure and expression of two nuclear receptor genes in marsupials: insights into the evolution of the antisense overlap between the α-thyroid hormone receptor and Rev-erbα

BACKGROUND: Alternative processing of α-thyroid hormone receptor (TRα, NR1A1) mRNAs gives rise to two functionally antagonistic nuclear receptors: TRα1, the α-type receptor, and TRα2, a non-hormone binding variant that is found only in mammals. TRα2 shares an unusual antisense coding overlap with mR...

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Detalles Bibliográficos
Autores principales: Rindfleisch, Brandon C, Brown, M Scott, VandeBerg, John L, Munroe, Stephen H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047299/
https://www.ncbi.nlm.nih.gov/pubmed/21143985
http://dx.doi.org/10.1186/1471-2199-11-97