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Aberrant methylation of Polo-like kinase CpG islands in Plk4 heterozygous mice

BACKGROUND: Hepatocellular carcinoma (HCC), one of the most common cancers world-wide occurs twice as often in men compared to women. Predisposing conditions such as alcoholism, chronic viral hepatitis, aflatoxin B1 ingestion, and cirrhosis all contribute to the development of HCC. METHODS: We used...

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Detalles Bibliográficos
Autores principales: Ward, Alejandra, Morettin, Alan, Shum, David, Hudson, John W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047422/
https://www.ncbi.nlm.nih.gov/pubmed/21324136
http://dx.doi.org/10.1186/1471-2407-11-71