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Aberrant methylation of Polo-like kinase CpG islands in Plk4 heterozygous mice
BACKGROUND: Hepatocellular carcinoma (HCC), one of the most common cancers world-wide occurs twice as often in men compared to women. Predisposing conditions such as alcoholism, chronic viral hepatitis, aflatoxin B1 ingestion, and cirrhosis all contribute to the development of HCC. METHODS: We used...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047422/ https://www.ncbi.nlm.nih.gov/pubmed/21324136 http://dx.doi.org/10.1186/1471-2407-11-71 |