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Improving Salmonella vector with rec mutation to stabilize the DNA cargoes

BACKGROUND: Salmonella has been employed to deliver therapeutic molecules against cancer and infectious diseases. As the carrier for target gene(s), the cargo plasmid should be stable in the bacterial vector. Plasmid recombination has been reduced in E. coli by mutating several genes including the r...

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Detalles Bibliográficos
Autores principales: Zhang, Xiangmin, Wanda, Soo-Young, Brenneman, Karen, Kong, Wei, Zhang, Xin, Roland, Kenneth, Curtiss, Roy
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047425/
https://www.ncbi.nlm.nih.gov/pubmed/21303535
http://dx.doi.org/10.1186/1471-2180-11-31