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Improving Salmonella vector with rec mutation to stabilize the DNA cargoes
BACKGROUND: Salmonella has been employed to deliver therapeutic molecules against cancer and infectious diseases. As the carrier for target gene(s), the cargo plasmid should be stable in the bacterial vector. Plasmid recombination has been reduced in E. coli by mutating several genes including the r...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047425/ https://www.ncbi.nlm.nih.gov/pubmed/21303535 http://dx.doi.org/10.1186/1471-2180-11-31 |