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Integration of lipidomics and transcriptomics data towards a systems biology model of sphingolipid metabolism

BACKGROUND: Sphingolipids play important roles in cell structure and function as well as in the pathophysiology of many diseases. Many of the intermediates of sphingolipid biosynthesis are highly bioactive and sometimes have antagonistic activities, for example, ceramide promotes apoptosis whereas s...

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Detalles Bibliográficos
Autores principales: Gupta, Shakti, Maurya, Mano R, Merrill Jr, Alfred H, Glass, Christopher K, Subramaniam, Shankar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047436/
https://www.ncbi.nlm.nih.gov/pubmed/21303545
http://dx.doi.org/10.1186/1752-0509-5-26