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Integration of lipidomics and transcriptomics data towards a systems biology model of sphingolipid metabolism
BACKGROUND: Sphingolipids play important roles in cell structure and function as well as in the pathophysiology of many diseases. Many of the intermediates of sphingolipid biosynthesis are highly bioactive and sometimes have antagonistic activities, for example, ceramide promotes apoptosis whereas s...
Autores principales: | Gupta, Shakti, Maurya, Mano R, Merrill Jr, Alfred H, Glass, Christopher K, Subramaniam, Shankar |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047436/ https://www.ncbi.nlm.nih.gov/pubmed/21303545 http://dx.doi.org/10.1186/1752-0509-5-26 |
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