Uracil DNA N-Glycosylase Promotes Assembly of Human Centromere Protein A

Uracil is removed from DNA by the conserved enzyme Uracil DNA N-glycosylase (UNG). Previously, we observed that inhibiting UNG in Xenopus egg extracts blocked assembly of CENP-A, a histone H3 variant. CENP-A is an essential protein in all species, since it is required for chromosome segregation duri...

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Detalles Bibliográficos
Autores principales: Zeitlin, Samantha G., Chapados, Brian R., Baker, Norman M., Tai, Caroline, Slupphaug, Geir, Wang, Jean Y. J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047565/
https://www.ncbi.nlm.nih.gov/pubmed/21399697
http://dx.doi.org/10.1371/journal.pone.0017151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047565/
https://www.ncbi.nlm.nih.gov/pubmed/21399697
http://dx.doi.org/10.1371/journal.pone.0017151

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