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A Single Base-Pair Change in 2009 H1N1 Hemagglutinin Increases Human Receptor Affinity and Leads to Efficient Airborne Viral Transmission in Ferrets

The 2009 H1N1 influenza A virus continues to circulate among the human population as the predominant H1N1 subtype. Epidemiological studies and airborne transmission studies using the ferret model have shown that the transmission efficiency of 2009 H1N1 viruses is lower than that of previous seasonal...

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Detalles Bibliográficos
Autores principales: Jayaraman, Akila, Pappas, Claudia, Raman, Rahul, Belser, Jessica A., Viswanathan, Karthik, Shriver, Zachary, Tumpey, Terrence M., Sasisekharan, Ram
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047569/
https://www.ncbi.nlm.nih.gov/pubmed/21407805
http://dx.doi.org/10.1371/journal.pone.0017616