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Alternative HER/PTEN/Akt Pathway Activation in HPV Positive and Negative Penile Carcinomas

BACKGROUND: The pathogenesis of penile squamous cell carcinoma (PSCC) is not well understood, though risk factors include human papillomavirus (HPV). Disruption of HER/PTEN/Akt pathway is present in many cancers; however there is little information on its function in PSCC. We investigated HER family...

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Detalles Bibliográficos
Autores principales: Stankiewicz, Elzbieta, Prowse, David M., Ng, Mansum, Cuzick, Jack, Mesher, David, Hiscock, Frances, Lu, Yong-Jie, Watkin, Nicholas, Corbishley, Catherine, Lam, Wayne, Berney, Daniel M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047574/
https://www.ncbi.nlm.nih.gov/pubmed/21407808
http://dx.doi.org/10.1371/journal.pone.0017517