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A Gene's Ability to Buffer Variation Is Predicted by Its Fitness Contribution and Genetic Interactions

BACKGROUND: Many single-gene knockouts result in increased phenotypic (e.g., morphological) variability among the mutant's offspring. This has been interpreted as an intrinsic ability of genes to buffer genetic and environmental variation. A phenotypic capacitor is a gene that appears to mask p...

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Detalles Bibliográficos
Autores principales: Wang, Guang-Zhong, Liu, Jian, Wang, Wei, Zhang, Hong-Yu, Lercher, Martin J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047586/
https://www.ncbi.nlm.nih.gov/pubmed/21407817
http://dx.doi.org/10.1371/journal.pone.0017650