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A Gene's Ability to Buffer Variation Is Predicted by Its Fitness Contribution and Genetic Interactions
BACKGROUND: Many single-gene knockouts result in increased phenotypic (e.g., morphological) variability among the mutant's offspring. This has been interpreted as an intrinsic ability of genes to buffer genetic and environmental variation. A phenotypic capacitor is a gene that appears to mask p...
Autores principales: | Wang, Guang-Zhong, Liu, Jian, Wang, Wei, Zhang, Hong-Yu, Lercher, Martin J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047586/ https://www.ncbi.nlm.nih.gov/pubmed/21407817 http://dx.doi.org/10.1371/journal.pone.0017650 |
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