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hERG potassium channel gating is mediated by N- and C-terminal region interactions
Human ether-á-go-go–related gene (hERG) potassium channels have voltage-dependent closing (deactivation) kinetics that are unusually slow. A Per-Arnt-Sim (PAS) domain in the cytoplasmic N-terminal region of hERG regulates slow deactivation by making a direct interaction with another part of the hERG...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047612/ https://www.ncbi.nlm.nih.gov/pubmed/21357734 http://dx.doi.org/10.1085/jgp.201010582 |