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hERG potassium channel gating is mediated by N- and C-terminal region interactions

Human ether-á-go-go–related gene (hERG) potassium channels have voltage-dependent closing (deactivation) kinetics that are unusually slow. A Per-Arnt-Sim (PAS) domain in the cytoplasmic N-terminal region of hERG regulates slow deactivation by making a direct interaction with another part of the hERG...

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Detalles Bibliográficos
Autores principales:	Gustina, Ahleah S., Trudeau, Matthew C.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047612/ https://www.ncbi.nlm.nih.gov/pubmed/21357734 http://dx.doi.org/10.1085/jgp.201010582

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