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Controversial data on simvastatin in asthma: What about the rat model?

The effects of simvastatin on lung inflammation in asthma are controversial. Reduction of inflammation and hyperreactivity has been reported in studies using murine models of asthma. In contrast, a clinical study has not found beneficial effects in patients. The rat model of asthma has some distinct...

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Detalles Bibliográficos
Autores principales: Tschernig, Thomas, Bäumer, Wolfgang, Pabst, Reinhard
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047916/
https://www.ncbi.nlm.nih.gov/pubmed/21437040