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Topiramate improves neurovascular function, epidermal nerve fiber morphology, and metabolism in patients with type 2 diabetes mellitus

PURPOSE: To assess the effects of topiramate on C-fiber function, nerve fiber morphology, and metabolism (including insulin sensitivity, obesity, and dyslipidemia) in type 2 diabetes. PATIENTS AND METHODS: We conducted an 18-week, open-label trial treating patients with topiramate. Twenty subjects w...

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Detalles Bibliográficos
Autores principales: Boyd, Amanda L, Barlow, Patricia M, Pittenger, Gary L, Simmons, Kathryn F, Vinik, Aaron I
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047986/
https://www.ncbi.nlm.nih.gov/pubmed/21437113
http://dx.doi.org/10.2147/DMSOTT.S13699