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Amantadine reduces glucagon and enhances insulin secretion throughout the oral glucose tolerance test: central plus peripheral nervous system mechanisms

OBJECTIVE: The purpose of the trial was to examine the effects of amantadine, a N-methyl-D-aspartate (NMDA) antagonist, on the oral glucose tolerance test (OGTT) plus insulin, glucagon and neurotransmitters circulating levels. Previous findings showed that hyperinsulinism and type 2 diabetes are pos...

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Detalles Bibliográficos
Autores principales: Lechin, Fuad, van der Dijs, Bertha, Pardey-Maldonado, Betty, Rivera, Jairo E, Lechin, Marcel E, Baez, Scarlet
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048001/
https://www.ncbi.nlm.nih.gov/pubmed/21437134