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Epidermal growth factor receptor gene copy number aberration at the primary tumour is significantly associated with extracapsular spread in oral cancer

BACKGROUND: Extracapsular spread (ECS) of lymph node metastasis in head and neck cancers, including oral squamous cell carcinomas (OSCCs), is known to reflect tumour aggressiveness, and is significantly associated with high rates of loco-regional recurrence, distant metastasis, and poor outcome. The...

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Detalles Bibliográficos
Autores principales: Michikawa, C, Uzawa, N, Sato, H, Ohyama, Y, Okada, N, Amagasa, T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048213/
https://www.ncbi.nlm.nih.gov/pubmed/21304522
http://dx.doi.org/10.1038/bjc.2011.22