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Differential Genetic Associations for Systemic Lupus Erythematosus Based on Anti–dsDNA Autoantibody Production

Systemic lupus erythematosus (SLE) is a clinically heterogeneous, systemic autoimmune disease characterized by autoantibody formation. Previously published genome-wide association studies (GWAS) have investigated SLE as a single phenotype. Therefore, we conducted a GWAS to identify genetic factors a...

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Detalles Bibliográficos
Autores principales: Chung, Sharon A., Taylor, Kimberly E., Graham, Robert R., Nititham, Joanne, Lee, Annette T., Ortmann, Ward A., Jacob, Chaim O., Alarcón-Riquelme, Marta E., Tsao, Betty P., Harley, John B., Gaffney, Patrick M., Moser, Kathy L., Petri, Michelle, Demirci, F. Yesim, Kamboh, M. Ilyas, Manzi, Susan, Gregersen, Peter K., Langefeld, Carl D., Behrens, Timothy W., Criswell, Lindsey A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048371/
https://www.ncbi.nlm.nih.gov/pubmed/21408207
http://dx.doi.org/10.1371/journal.pgen.1001323