Training Signaling Pathway Maps to Biochemical Data with Constrained Fuzzy Logic: Quantitative Analysis of Liver Cell Responses to Inflammatory Stimuli

Predictive understanding of cell signaling network operation based on general prior knowledge but consistent with empirical data in a specific environmental context is a current challenge in computational biology. Recent work has demonstrated that Boolean logic can be used to create context-specific...

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Detalles Bibliográficos
Autores principales: Morris, Melody K., Saez-Rodriguez, Julio, Clarke, David C., Sorger, Peter K., Lauffenburger, Douglas A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048376/
https://www.ncbi.nlm.nih.gov/pubmed/21408212
http://dx.doi.org/10.1371/journal.pcbi.1001099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048376/
https://www.ncbi.nlm.nih.gov/pubmed/21408212
http://dx.doi.org/10.1371/journal.pcbi.1001099

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