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Sumoylation of Hypoxia-Inducible Factor-1α Ameliorates Failure of Brain Stem Cardiovascular Regulation in Experimental Brain Death

BACKGROUND: One aspect of brain death is cardiovascular deregulation because asystole invariably occurs shortly after its diagnosis. A suitable neural substrate for mechanistic delineation of this aspect of brain death resides in the rostral ventrolateral medulla (RVLM). RVLM is the origin of a life...

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Detalles Bibliográficos
Autores principales: Chan, Julie Y. H., Tsai, Ching-Yi, Wu, Carol H. Y., Li, Faith C. H., Dai, Kuang-Yu, Sun, Enya Y. H., Chan, Samuel H. H., Chang, Alice Y. W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048406/
https://www.ncbi.nlm.nih.gov/pubmed/21390240
http://dx.doi.org/10.1371/journal.pone.0017375