Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner

BACKGROUND: Fanconi anemia (FA) is a rare autosomal recessive syndrome characterized by developmental abnormalities, progressive bone marrow failure, and predisposition to cancer. The key FA protein FANCD2 crosstalks with members of DNA damage and repair pathways that also play a role at telomeres....

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Detalles Bibliográficos
Autores principales: Lyakhovich, Alex, Ramirez, Maria Jose, Castellanos, Andres, Castella, Maria, Simons, Amanda M, Parvin, Jeffrey D, Surralles, Jordi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048478/
https://www.ncbi.nlm.nih.gov/pubmed/21314979
http://dx.doi.org/10.1186/2041-9414-2-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048478/
https://www.ncbi.nlm.nih.gov/pubmed/21314979
http://dx.doi.org/10.1186/2041-9414-2-4

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