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Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner
BACKGROUND: Fanconi anemia (FA) is a rare autosomal recessive syndrome characterized by developmental abnormalities, progressive bone marrow failure, and predisposition to cancer. The key FA protein FANCD2 crosstalks with members of DNA damage and repair pathways that also play a role at telomeres....
Autores principales: | Lyakhovich, Alex, Ramirez, Maria Jose, Castellanos, Andres, Castella, Maria, Simons, Amanda M, Parvin, Jeffrey D, Surralles, Jordi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048478/ https://www.ncbi.nlm.nih.gov/pubmed/21314979 http://dx.doi.org/10.1186/2041-9414-2-4 |
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