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Differential utilization of NF-kappaB RELA and RELB in response to extracellular versus intracellular polyIC stimulation in HT1080 cells

BACKGROUND: Pattern recognition receptors (PRRs) for double-stranded RNA (dsRNA) are components of innate immunity that recognize the presence of viral infection and initiate efficient defense mechanisms. In addition to previously well-characterized signaling pathways that are mediated by PKR and TL...

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Detalles Bibliográficos
Autores principales: Yun, James J, Tsao, Ming-Sound, Der, Sandy D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048558/
https://www.ncbi.nlm.nih.gov/pubmed/21310030
http://dx.doi.org/10.1186/1471-2172-12-15