Cargando…
Fungal Recognition Enhances Mannose Receptor Shedding through Dectin-1 Engagement
The mannose receptor (MR) is an endocytic type I membrane molecule with a broad ligand specificity that is involved in both hemostasis and pathogen recognition. Membrane-anchored MR is cleaved by a metalloproteinase into functional soluble MR (sMR) composed of the extracellular domains of intact MR....
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048669/ https://www.ncbi.nlm.nih.gov/pubmed/21205820 http://dx.doi.org/10.1074/jbc.M110.185025 |