Macrocyclic β-Sheet Peptides That Inhibit the Aggregation of a Tau-Protein-Derived Hexapeptide

[Image: see text] This paper describes studies of a series of macrocyclic β-sheet peptides 1 that inhibit the aggregation of a tau-protein-derived peptide. The macrocyclic β-sheet peptides comprise a pentapeptide “upper” strand, two δ-linked ornithine turn units, and a “lower” strand comprising two...

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Detalles Bibliográficos
Autores principales: Zheng, Jing, Liu, Cong, Sawaya, Michael R., Vadla, Balraju, Khan, Shafiullah, Woods, R. Jeremy, Eisenberg, David, Goux, Warren J., Nowick, James S.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048834/
https://www.ncbi.nlm.nih.gov/pubmed/21319744
http://dx.doi.org/10.1021/ja110545h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048834/
https://www.ncbi.nlm.nih.gov/pubmed/21319744
http://dx.doi.org/10.1021/ja110545h

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