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Characterisation of the macrophage transcriptome in glomerulonephritis-susceptible and -resistant rat strains

Crescentic glomerulonephritis (CRGN) is a major cause of rapidly progressive renal failure for which the underlying genetic basis is unknown. WKY rats show marked susceptibility to CRGN, while Lewis rats are resistant. Glomerular injury and crescent formation are macrophage-dependent and mainly expl...

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Detalles Bibliográficos
Autores principales: Maratou, Klio, Behmoaras, Jacques, Fewings, Chris, Srivastava, Prashant, D’Souza, Zelpha, Smith, Jennifer, Game, Laurence, Cook, Terence, Aitman, Tim
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048856/
https://www.ncbi.nlm.nih.gov/pubmed/21179115
http://dx.doi.org/10.1038/gene.2010.61