IL-1β Stimulates COX-2 Dependent PGE(2) Synthesis and CGRP Release in Rat Trigeminal Ganglia Cells

OBJECTIVE: Pro-inflammatory cytokines like Interleukin-1 beta (IL-1β) have been implicated in the pathophysiology of migraine and inflammatory pain. The trigeminal ganglion and calcitonin gene-related peptide (CGRP) are crucial components in the pathophysiology of primary headaches. 5-HT1B/D recepto...

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Detalles Bibliográficos
Autores principales: Neeb, Lars, Hellen, Peter, Boehnke, Carsten, Hoffmann, Jan, Schuh-Hofer, Sigrid, Dirnagl, Ulrich, Reuter, Uwe
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048859/
https://www.ncbi.nlm.nih.gov/pubmed/21394197
http://dx.doi.org/10.1371/journal.pone.0017360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048859/
https://www.ncbi.nlm.nih.gov/pubmed/21394197
http://dx.doi.org/10.1371/journal.pone.0017360

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