Cargando…

IL-1β Stimulates COX-2 Dependent PGE(2) Synthesis and CGRP Release in Rat Trigeminal Ganglia Cells

OBJECTIVE: Pro-inflammatory cytokines like Interleukin-1 beta (IL-1β) have been implicated in the pathophysiology of migraine and inflammatory pain. The trigeminal ganglion and calcitonin gene-related peptide (CGRP) are crucial components in the pathophysiology of primary headaches. 5-HT1B/D recepto...

Descripción completa

Detalles Bibliográficos
Autores principales:	Neeb, Lars, Hellen, Peter, Boehnke, Carsten, Hoffmann, Jan, Schuh-Hofer, Sigrid, Dirnagl, Ulrich, Reuter, Uwe
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048859/ https://www.ncbi.nlm.nih.gov/pubmed/21394197 http://dx.doi.org/10.1371/journal.pone.0017360

Ejemplares similares

Methylprednisolone blocks interleukin 1 beta induced calcitonin gene related peptide release in trigeminal ganglia cells
por: Neeb, Lars, et al.
Publicado: (2016)

miR‐34a‐5p up‐regulates the IL‐1β/COX2/PGE2 inflammation pathway and induces the release of CGRP via inhibition of SIRT1 in rat trigeminal ganglion neurons
por: Zhang, Hui, et al.
Publicado: (2020)

CGRP and the Calcitonin Receptor are Co-Expressed in Mouse, Rat and Human Trigeminal Ganglia Neurons
por: Rees, Tayla A., et al.
Publicado: (2022)

IL-33 facilitates proliferation of colorectal cancer dependent on COX2/PGE(2)
por: Li, Yongkui, et al.
Publicado: (2018)

CGRP and the Trigeminal System in Migraine
por: Iyengar, Smriti, et al.
Publicado: (2019)

Methyprednisolone i.v. alters levels of CGRP and melatonin in cluster headache patients
por: Neeb, L, et al.
Publicado: (2013)

CGRP Induces Differential Regulation of Cytokines from Satellite Glial Cells in Trigeminal Ganglia and Orofacial Nociception
por: Afroz, Shaista, et al.
Publicado: (2019)

COX-2-PGE(2)-EPs in gynecological cancers
por: Ye, Yao, et al.
Publicado: (2020)

Correction to: IL-33 facilitates proliferation of colorectal cancer dependent on COX2/PGE(2)
por: Li, Yongkui, et al.
Publicado: (2020)

Role of CGRP in Neuroimmune Interaction via NF-κB Signaling Genes in Glial Cells of Trigeminal Ganglia
por: Afroz, Shaista, et al.
Publicado: (2020)

Effect of Electroacupuncture Intervention on Expression of CGRP, SP, COX-1, and PGE2 of Dorsal Portion of the Cervical Spinal Cord in Rats with Neck-Incision Pain
por: Qiao, Li-na, et al.
Publicado: (2013)

Two TRPV1 receptor antagonists are effective in two different experimental models of migraine
por: Meents, Jannis E, et al.
Publicado: (2015)

Migraine evolution after the cessation of CGRP(-receptor) antibody prophylaxis: a prospective, longitudinal cohort study
por: Raffaelli, Bianca, et al.
Publicado: (2021)

Role of TRPV-1 in CGRP-mediated trigeminal sensitization
por: Chatchaisak, D, et al.
Publicado: (2013)

Expression of the CGRP Family of Neuropeptides and their Receptors in the Trigeminal Ganglion
por: Edvinsson, Lars, et al.
Publicado: (2020)

CGRP release in an experimental human trigeminal pain model
por: Frese, Achim, et al.
Publicado: (2021)

Indirect Comparison of Topiramate and Monoclonal Antibodies Against CGRP or Its Receptor for the Prophylaxis of Episodic Migraine: A Systematic Review with Meta-Analysis
por: Overeem, Lucas Hendrik, et al.
Publicado: (2021)

Regulated Expression of PTPRJ by COX-2/PGE(2) Axis in Endothelial Cells
por: Xu, Xiaobing, et al.
Publicado: (2014)

Pleiotropic effects of the COX-2/PGE2 axis in the glioblastoma tumor microenvironment
por: Dean, Phillip T., et al.
Publicado: (2023)

The Anti-Calcitonin Gene-Related Peptide (Anti-CGRP) Antibody Fremanezumab Reduces Trigeminal Neurons Immunoreactive to CGRP and CGRP Receptor Components in Rats
por: Vogler, Birgit, et al.
Publicado: (2023)

Formononetin inhibits enterovirus 71 replication by regulating COX- 2/PGE(2) expression
por: Wang, Huiqiang, et al.
Publicado: (2015)

Role of COX-2/PGE2 Mediated Inflammation in Oral Squamous Cell Carcinoma
por: Nasry, Walaa Hamed Shaker, et al.
Publicado: (2018)

Improving VEGF-targeted therapies through inhibition of COX-2/PGE(2) signaling
por: Xu, Lihong, et al.
Publicado: (2014)

COX2 regulates senescence secretome composition and senescence surveillance through PGE(2)
por: Gonçalves, Susana, et al.
Publicado: (2021)

Dedifferentiation of Human Cardiac Myofibroblasts Is Independent of Activation of COX-2/PGE(2) Pathway
por: Luu, Vy Tran, et al.
Publicado: (2022)

COX-2/PGE2 upregulation contributes to the chromosome 17p-deleted lymphoma
por: Qi, Lu, et al.
Publicado: (2023)

Deterioration of headache impact and health-related quality of life in migraine patients after cessation of preventive treatment with CGRP(−receptor) antibodies
por: Terhart, Maria, et al.
Publicado: (2021)

Resumption of migraine preventive treatment with CGRP(-receptor) antibodies after a 3-month drug holiday: a real-world experience
por: Raffaelli, Bianca, et al.
Publicado: (2022)

Effect of COX-2 inhibition on tendon-to-bone healing and PGE2 concentration after anterior cruciate ligament reconstruction
por: Sauerschnig, Martin, et al.
Publicado: (2018)

Plasma calcitonin gene‐related peptide (CGRP) in migraine and endometriosis during the menstrual cycle
por: Raffaelli, Bianca, et al.
Publicado: (2021)

Neuropeptide FF receptor 2 inhibits capsaicin-induced CGRP Upregulation in mouse trigeminal ganglion
por: Lin, Ya-Tin, et al.
Publicado: (2020)

Involvement of COX-2/PGE(2) Pathway in the Upregulation of MMP-9 Expression in Pancreatic Cancer
por: Bu, Xianmin, et al.
Publicado: (2011)

Involvement of COX-2/PGE(2) signalling in hypoxia-induced angiogenic response in endothelial cells
por: Zhao, Lixing, et al.
Publicado: (2012)

The Role of COX-2 and PGE2 in the Regulation of Immunomodulation and Other Functions of Mesenchymal Stromal Cells
por: Kulesza, Agnieszka, et al.
Publicado: (2023)

Growth and adherence of Staphylococcus aureus were enhanced through the PGE(2) produced by the activated COX-2/PGE(2) pathway of infected oral epithelial cells
por: Wang, Yuxia, et al.
Publicado: (2017)

Influence of varying estrogen levels on trigeminal CGRP release in healthy women
por: Ibrahimi, K, et al.
Publicado: (2013)

Korean Red Ginseng affects ovalbumin-induced asthma by modulating IL-12, IL-4, and IL-6 levels and the NF-κB/COX-2 and PGE(2) pathways
por: Lee, Soon-Young, et al.
Publicado: (2021)

NDRG2 Controls COX-2/PGE(2)-Mediated Breast Cancer Cell Migration and Invasion
por: Kim, Myung-Jin, et al.
Publicado: (2014)

Change of CGRP Plasma Concentrations in Migraine after Discontinuation of CGRP-(Receptor) Monoclonal Antibodies
por: Raffaelli, Bianca, et al.
Publicado: (2023)

Effect of antibody switch in non-responders to a CGRP receptor antibody treatment in migraine: A multi-center retrospective cohort study
por: Overeem, Lucas Hendrik, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_sf72sdgilvlplnna95j5tn1n5g