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Inhibition of spontaneous activity of rabbit atrioventricular node cells by KB-R7943 and inhibitors of sarcoplasmic reticulum Ca(2+) ATPase

The atrioventricular node (AVN) can act as a subsidiary cardiac pacemaker if the sinoatrial node fails. In this study, we investigated the effects of the Na–Ca exchange (NCX) inhibitor KB-R7943, and inhibition of the sarcoplasmic reticulum calcium ATPase (SERCA), using thapsigargin or cyclopiazonic...

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Detalles Bibliográficos
Autores principales: Cheng, Hongwei, Smith, Godfrey L., Hancox, Jules C., Orchard, Clive H.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048929/
https://www.ncbi.nlm.nih.gov/pubmed/21163524
http://dx.doi.org/10.1016/j.ceca.2010.11.008