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The ADP receptor P2Y(1 )is necessary for normal thermal sensitivity in cutaneous polymodal nociceptors

BACKGROUND: P2Y(1 )is a member of the P2Y family of G protein-coupled nucleotide receptors expressed in peripheral sensory neurons. Using ratiometric calcium imaging of isolated dorsal root ganglion neurons, we found that the majority of neurons responding to adenosine diphosphate, the preferred end...

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Detalles Bibliográficos
Autores principales: Molliver, Derek C, Rau, Kristofer K, McIlwrath, Sabrina L, Jankowski, Michael P, Koerber, H Richard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049184/
https://www.ncbi.nlm.nih.gov/pubmed/21310055
http://dx.doi.org/10.1186/1744-8069-7-13