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Deciphering the nuclear bile acid receptor FXR paradigm
Originally called retinoid X receptor interacting protein 14 (RIP14), the farnesoid X receptor (FXR) was renamed after the ability of its rat form to bind supra-physiological concentrations of farnesol. In 1999 FXR was de-orphanized since primary bile acids were identified as natural ligands. Strong...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Nuclear Receptor Signaling Atlas
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049226/ https://www.ncbi.nlm.nih.gov/pubmed/21383957 http://dx.doi.org/10.1621/nrs.08005 |