Mutual information identifies sequence positions conserved within the nuclear receptor superfamily: approach reveals functionally important regions for DNA binding specificity

Members of the nuclear receptor superfamily differentiate in terms of specificity for DNA recognition and binding, oligomeric state, and ligand binding. The wide range of specificities are impressive given the high degree of sequence conservation in the DNA binding domain (DBD) and moderate sequence...

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Detalles Bibliográficos
Autores principales: Willis, Scooter, Griffin, Patrick R.
Formato: Texto
Lenguaje:English
Publicado: The Nuclear Receptor Signaling Atlas 2011
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049237/
https://www.ncbi.nlm.nih.gov/pubmed/21383938
http://dx.doi.org/10.1621/nrs.09001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049237/
https://www.ncbi.nlm.nih.gov/pubmed/21383938
http://dx.doi.org/10.1621/nrs.09001

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