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Transcriptional repression and DNA looping associated with a novel regulatory element in the final exon of the lymphotoxin-β gene

Transcriptional regulation has a critical role in the coordinate and context-specific expression of a cluster of genes encoding members of the tumour necrosis factor (TNF) superfamily found at chromosome 6p21, comprising TNF, LTA (encoding lymphotoxin-α) and LTB (encoding lymphotoxin-β). This is imp...

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Detalles Bibliográficos
Autores principales: Wicks, K, Knight, J C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049238/
https://www.ncbi.nlm.nih.gov/pubmed/21248773
http://dx.doi.org/10.1038/gene.2010.62