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Role of protein kinase C β and vascular endothelial growth factor receptor in malignant pleural mesothelioma: Therapeutic implications and the usefulness of Caenorhabditis elegans model organism

PURPOSE: To examine the role of both protein kinase C (PKC)-β and vascular endothelial growth factor receptor (VEGFR)-2 in malignant pleural mesothelioma (MPM) using respective inhibitors, enzastaurin and KRN633. MATERIALS AND METHODS: MPM cell lines, control cells, and a variety of archived MPM tum...

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Detalles Bibliográficos
Autores principales: Loganathan, Sivakumar, Kanteti, Rajani, Siddiqui, Shahid S., El-Hashani, Essam, Tretiakova, Maria, Vigneswaran, Hari, Cervantes, Gustavo, Natarajan, Viswanathan, Husain, Aliya N., Vokes, Everett E., Kindler, Hedy L., Salgia, Ravi
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049271/
https://www.ncbi.nlm.nih.gov/pubmed/21383961
http://dx.doi.org/10.4103/1477-3163.77274