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The Caspase Pathway as a Possible Therapeutic Target in Experimental Pemphigus

Apoptosis plays a role in pemphigus IgG-dependent acantholysis; theoretically, the blockade of the caspase pathway could prevent the blistering that is caused by pemphigus autoantibodies. Using this strategy, we attempted to block the pathogenic effect of pemphigus IgG in Balb/c mice by using the ca...

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Detalles Bibliográficos
Autores principales: Pacheco-Tovar, Deyanira, López-Luna, Argelia, Herrera-Esparza, Rafael, Avalos-Díaz, Esperanza
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049334/
https://www.ncbi.nlm.nih.gov/pubmed/21403857
http://dx.doi.org/10.4061/2011/563091