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Glyburide Is Anti-inflammatory and Associated with Reduced Mortality in Melioidosis

Background. Patients with diabetes mellitus are more prone to bacterial sepsis, but there are conflicting data on whether outcomes are worse in diabetics after presentation with sepsis. Glyburide is an oral hypoglycemic agent used to treat diabetes mellitus. This K(ATP)-channel blocker and broad-spe...

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Detalles Bibliográficos
Autores principales: Koh, Gavin C. K. W., Maude, Rapeephan R., Schreiber, M. Fernanda, Limmathurotsakul, Direk, Wiersinga, W. Joost, Wuthiekanun, Vanaporn, Lee, Sue J., Mahavanakul, Weera, Chaowagul, Wipada, Chierakul, Wirongrong, White, Nicholas J., van der Poll, Tom, Day, Nicholas P. J., Dougan, Gordon, Peacock, Sharon J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049341/
https://www.ncbi.nlm.nih.gov/pubmed/21293047
http://dx.doi.org/10.1093/cid/ciq192