Epitope mapping and key amino acid identification of anti-CD22 immunotoxin CAT-8015 using hybrid β-lactamase display

Monoclonal antibodies are a commercially successful class of drug molecules and there are now a growing number of antibodies coupled to toxic payloads, which demonstrate clinical efficacy. Determining the precise epitope of therapeutic antibodies is beneficial in understanding the structure–activity...

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Detalles Bibliográficos
Autores principales: Bannister, D., Popovic, B., Sridharan, S., Giannotta, F., Filée, P., Yilmaz, N., Minter, R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049344/
https://www.ncbi.nlm.nih.gov/pubmed/21159620
http://dx.doi.org/10.1093/protein/gzq114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049344/
https://www.ncbi.nlm.nih.gov/pubmed/21159620
http://dx.doi.org/10.1093/protein/gzq114

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