Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast

To obtain rates of mRNA synthesis and decay in yeast, we established dynamic transcriptome analysis (DTA). DTA combines non-perturbing metabolic RNA labeling with dynamic kinetic modeling. DTA reveals that most mRNA synthesis rates are around several transcripts per cell and cell cycle, and most mRN...

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Detalles Bibliográficos
Autores principales: Miller, Christian, Schwalb, Björn, Maier, Kerstin, Schulz, Daniel, Dümcke, Sebastian, Zacher, Benedikt, Mayer, Andreas, Sydow, Jasmin, Marcinowski, Lisa, Dölken, Lars, Martin, Dietmar E, Tresch, Achim, Cramer, Patrick
Formato: Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049410/
https://www.ncbi.nlm.nih.gov/pubmed/21206491
http://dx.doi.org/10.1038/msb.2010.112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049410/
https://www.ncbi.nlm.nih.gov/pubmed/21206491
http://dx.doi.org/10.1038/msb.2010.112

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