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Neuroprotective signaling pathways are modulated by adenosine in the anoxia tolerant turtle

Cumulative evidence shows a protective role for adenosine A1 receptors (A1R) in hypoxia/ischemia; A1R stimulation reduces neuronal damage, whereas blockade exacerbates damage. The signal transduction pathways may involve the mitogen-activated protein kinase (MAPK) pathways and serine/threonine kinas...

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Detalles Bibliográficos
Autores principales: Nayak, Gauri H, Prentice, Howard M, Milton, Sarah L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049502/
https://www.ncbi.nlm.nih.gov/pubmed/20648037
http://dx.doi.org/10.1038/jcbfm.2010.109