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Neuroprotective signaling pathways are modulated by adenosine in the anoxia tolerant turtle
Cumulative evidence shows a protective role for adenosine A1 receptors (A1R) in hypoxia/ischemia; A1R stimulation reduces neuronal damage, whereas blockade exacerbates damage. The signal transduction pathways may involve the mitogen-activated protein kinase (MAPK) pathways and serine/threonine kinas...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049502/ https://www.ncbi.nlm.nih.gov/pubmed/20648037 http://dx.doi.org/10.1038/jcbfm.2010.109 |